Early research shows that taking sea buckthorn pulp oil by mouth for 4 months improves atopic dermatitis. However, sea buckthorn seed oil taken by mouth does not have this effect. Also, applying cream containing 10% or 20% sea buckthorn on the skin for 4 weeks does not seem to improve symptoms of mild-to-moderate atopic dermatitis. Early research shows that taking a specific combination supplement containing sea buckthorn berry oil and other ingredients by mouth might improve wrinkles and sun-damaged skin when used along with a skin cream containing 0.1% tazarotene.